Pregnancy and breast-feeding: There isn't enough reliable information to know if acetyl-L-carnitine is safe to use when pregnant or breast-feeding. It's not clear if taking acetyl-L-carnitine alone helps. Taking acetyl-L-carnitine by mouth along with L-carnitine seems to increase sperm count and sperm movement in males with fertility problems.

Conditions in a male that prevent a female partner from getting pregnant (male infertility).

Taking acetyl-L-carnitine by mouth 2-3 grams daily seems to improve symptoms in people with nerve pain caused by diabetes.

Nerve pain in people with diabetes ( diabetic neuropathy).

It seems to work better in older people and when taken in higher amounts. Taking 1-4 grams of acetyl-L-carnitine by mouth daily seems to improve mood and decrease depression in some people. Taking acetyl-L-carnitine by mouth might slow the rate of disease progression, improve memory, and improve some measures of mental function and behavior in some people with Alzheimer disease. But it's possible that the benefits are from IV acetyl-L-carnitine only. Acetyl-L-carnitine given intravenously (by IV) for 10 days and then taken by mouth for 80 days, helps reduce withdrawal symptoms and cravings during alcohol detox. It also seems to reduce tiredness after exercise.

Taking acetyl-L-carnitine by mouth might improve mental and physical tiredness in older people.

Taking acetyl-L-carnitine by mouth might improve memory and mental function in older people with some memory loss. Decline in memory and thinking skills that occurs normally with age.

Breath by S. Atzeni